Duke vs. TCU odds, March Madness predictions: 2026 NCAA Tournament picks from proven model The ninth-seeded Texas Christian Horned Frogs will face the top-seeded Duke Blue Devils in the second round of the 2026 NCAA Tournament East Region on Saturday. TCU secured its spot with a 66-64 victory over eighth-seeded Ohio State on Thursday, while Duke advanced after a 71-65 win against 16th-seeded Siena. The Horned Frogs, who finished sixth in the Big 12 with a 11-7 record, have won seven of their last eight games. Duke, the ACC regular season champion with a 17-1 record, has now won 12 consecutive games. Duke is missing starting forward Caleb Foster due to a foot injury, and center Patrick Ngongba is listed as questionable. The game will take place at the Bon Secours Wellness Arena in Greenville, South Carolina, with a tipoff time of 5:15 p.m. ET. Duke is currently listed as an 11.5-point favorite in the latest odds, while the total points scored are projected to be 140.5. SportsLine’s Projection Model, which has a strong track record of accurate college basketball predictions, has simulated the matchup 10,000 times and released its findings. The model’s analysis suggests the Over on the total points is the most likely outcome, as the Over has hit in two of the last three TCU games and six of the last 10 Duke games. TCU is 8-2 against the spread in its last 10 contests, while Duke is 6-4 ATS in the same span. The model projects TCU to have two players scoring 11 or more points, with David Punch expected to contribute 11.9 points. Duke is projected to have three players scoring 11.4 points or more, led by Cameron Boozer, who is predicted to score 25 points. The model’s total combined score for the game is 148 points.#duke_blue_devils #tcu_horned_frogs #sportsline #bon_secours_wellness_arena #greenville_south_carolina
