GSK to Acquire U.S. Cancer Drugmaker Nuvalent for $10.6 Billion GlaxoSmithKline (GSK), the U.K. pharmaceutical giant, has agreed to acquire U.S.-based oncology biotech Nuvalent for $10.6 billion in an all-cash deal. The transaction, which values Nuvalent at approximately $124 per share—a 40% premium to its last closing price—marks GSK’s largest acquisition in over a decade. The deal is expected to bolster GSK’s oncology pipeline and address declining revenue from its HIV medication, which will lose exclusivity in 2028. Nuvalent’s shares surged 39% in premarket trading, while GSK’s stock dipped 2.6% in London following the announcement. The acquisition includes Nuvalent’s two late-stage lung cancer treatments, which GSK described as having “blockbuster potential.” These therapies, zidesamtinib and neladalkib, are designed for specific genetic mutations in non-small cell lung cancer and are currently under FDA review. The deal also encompasses an early-stage medicine and Nuvalent’s preclinical portfolio. GSK CEO Luke Miels emphasized the strategic value of the acquisition, stating it would provide “immediate new sales growth opportunities” and offer significant treatment options for patients with two forms of lung cancer. Analysts at Barclays acknowledged the deal’s potential to accelerate GSK’s entry into the lung cancer space but questioned whether the two late-stage assets would achieve “mega blockbuster” status. They noted the upside for zidesamtinib and neladalkib was “capped” and highlighted the importance of the acquisition in offsetting revenue losses from the HIV drug’s patent expiration, which is projected to impact GSK starting mid-2028. The company reiterated that its 2026 financial guidance remains unchanged, with the acquisition expected to contribute to revenue growth beginning in 2027.#london #lung_cancer #gsk #nuvalent #ros1_positive_non_small_cell_lung_cancer
Kathy Griffin Hospitalized After Colonoscopy Complications Kathy Griffin, the comedian and television personality, revealed she was hospitalized overnight due to complications following a colonoscopy, sharing the news in a candid Instagram post. The 65-year-old star described the situation as “TMI” (too much information) in her update, writing, “I spent the night in the hospital because I had complications from my colonoscopy.” She added, “I know, I know, very sexy but I am home now with the doggies where I belongs.” The post, shared on Thursday, included a selfie captioned “A not so tech savvy update,” which prompted a wave of supportive comments from followers. Griffin’s health struggles have been a recurring topic in her public life. In August 2021, she opened up about her past battles with prescription drug addiction during an interview with ABC’s Nightline. She detailed hitting a breaking point in early 2020, when suicidal thoughts became “obsessive.” She recounted planning her own death, including drafting a note and organizing her affairs, before seeking help. At the time, she also disclosed a lung cancer diagnosis, despite never having smoked. She announced in December 2021 that she was “cancer-free” after undergoing surgery to remove half of her left lung. The comedian noted that her voice had changed post-surgery, joking that it was now “a good two octaves higher” than Mariah Carey’s. Reflecting on her journey, she admitted the cancer surgery was “a little more than I had anticipated.” Griffin also referenced her previous hospitalization, which occurred during a suicide attempt involving prescription pills. She praised her progress, stating, “With over a year clean and drug free, I now know I can do this and anything I want without those devil pills.#lung_cancer #instagram #kathy_griffin #nightline #prescription_drugs
AIIMS-Delhi to study link between lung cancer and air pollution #lung_cancer #air_pollution #study_link #AIIMS-Delhi #pollution
India releases first national lung cancer care guidelines ahead of World Cancer Day India has launched its first nationally developed, evidence-based guidelines for lung cancer treatment and palliation. These guidelines aim to standardize care, improve early diagnosis, and reduce treatment gaps across the country. They offer a common clinical framework for both public and private healthcare systems, emphasizing patient-centric care and quality of life. #cancer #Day_India #World_Cancer #Cancer_Day #lung_cancer #India_releases #nationally_developed #national_lung #cancer_treatment #evidence-based_guidelines
